For the most part yes but there are some considerations particularly with the Saitel Switch Panel. The switch panel has rocker switches which are in a fixed position until you change them. If you try to control those functions with X-KeyPad it is possible that the plugin driving the Saitek Panel will simply force the simulator state back to whatever position the hardware switch is in.
This is not such a big problem with the other Saitek Panels as they are mostly stateless with the exception of the Auto Throttle Arm on the Multi-Panel.
